Case Study Links

1. Introduction 2. Interview 3. Physical Examination 4. Lab Tests Contact Lynda
Biology 170: Human Pathophysiology -- Case Studies -- Instructor: Lynda C. Titterington

Ritta DePaolo: Lab Tests

NOTE: Remember that unnecessary laboratory testing wastes precious time and increases health costs for all of us!

Laboratory test results:

Cerebrospinal fluid (CSF) examination
Blood Negative
Color Clear and colorless
Lymphocytes 0-2/mm3 (Normal: <5/mm3)
Polymorphonuclear lymphocytes None (Normal: none)
Protein 80 mg/dl (normal: 15-45 mg/dl)
Glucose 50 mg/dl (Normal: 50-75 mg/dl)
Chloride 115 mEq/l (Normal: 110 to 125 mEq per liter)
Cytology No evidence of malignant cells
Serologic test for venereal disease Negative (Normal: negative)

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Questions:

Please email your answers to your instructor or write the answers down in your case log book. NOTE: For multiple choice questions, clicking on the word or phrase will provide feedback.

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1. What potential causes of Ms. DePaolo's headaches were ruled out or confirmed by the skull x-ray?
2. The increased intracranial pressure (ICP) indicated by the lumbar puncture may indicatea(n) ____________. (Select all answers that apply).
Brain tumor
Infectious brain disease (i.e. encephalitis or meningitis)
Migraine headache
Subarachnoid hematoma
3. Cerebrospinal fluid analysis excluded the possibility of _____. (Select all answers that apply.)
A brain tumor
Migraine headache
Infectious brain disease (i.e. meningitis or encephalitis)
Subarachnoid hemorrhage
4. Why are computerized tomography (CT) and magnetic resonance imaging (MRI) useful techniques for the diagnosis of a brain tumor?
5. Do the laboratory results confirm your preliminary assessment? Which neurological disorder(s)is/are affecting Ms. DePaolo? Select all that apply.
A brain tumor
Infectious brain disease
Migraine headache
Subarachnoid hemorrhage
6. How is the pathophysiology and symptoms of a migraine headache different from these headaches? Please list three distinguishing features for each type of headache.
Encephalitis
Headache associated with head trauma
Sinus headache
Tension-type headache
7. Ms. DePaolo was diagnosed with a benign meningioma that was surgically removed. List 4 characteristics of benign tumors.
Bonus: Ms. DePaolo's physical examination indicated papilledema, which is a sign of increased intracranial pressure. In real life, lumbar punctures are avoided if there is any evidence of increased ICP. Why is that?

    

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